Chemistry & Medicine

What are protein condensates? Biomolecular condensates are small ‘compartments’ created inside cells without any membrane playing key roles to organise myriad biochemical reactions. Unlike typical cell structures, these condensates are formed due to a process called liquid-liquid phase separation, where specific proteins clump together (like oil droplets in water). This phenomenon is studied worldwide but how exactly the sequence of amino acids in these proteins defines the

BACKGROUND Over the past two decades, G protein‑coupled receptors (GPCRs) have emerged as one of the most intensively studied drug target families, underpinning therapies across cardiovascular, metabolic, neurological and oncological disease. Conventional small‑molecule and peptide ligands, however, often struggle to achieve the desired selectivity and signaling precision for individual GPCR subtypes or conformational states. Antibodies offer a way to overcome these limitatio

23 June 2025 A recent but major breakthrough in developmental and reproductive biology along with regenerative medicine is the ex vivo generation of synthetic human embryos without the need for a sperm or egg from stem cells long enough for some organs to develop. It represents a revolutionary leap in science that opens up a whole new series of ethical, regulatory, and societal debates. A new world where life is reimagined in a laboratory using advanced stem cell techniques.

A nine-year collaborative project involving teams from the South Australian Health and Medical Research Institute (SAHMRI), The University of Adelaide, Baker Heart and Diabetes Institute, and La Trobe University has recently culminated in a groundbreaking discovery. The team has identified a new type of progenitor cell, EndoMac progenitor, which holds great promise for advancing regenerative wound healing applications. Dr. Sanuri Liyanage from SAHMRI highlighted the remarkab